Alexandre Borrel

I did not intend to pursue a career in cheminformatics as I originally began in the field of bioinformatics. Where my career has taken me today is the result of meeting and collaborating with interesting people that inspirited me. During my second year at the College of Grenoble, I became interested in chemistry when my quantum chemistry professor, Prof. Andre Grand, showed me a quantum model developed to analyze DNA mutation. His enthusiasm about his research in quantum chemistry inspired a growing passion of my own for studying chemical systems with a computational approach. Then, while studying genomic bioinformatics during my Master's degree I participated as an exchange student with the University of Helsinki. During this internship I joined the lab of Dr. Xhaard. This internship had a significant impact on my career as it inspired me to pursue a Ph. D. in cheminformatics. My Ph. D. work would consist of a joint thesis between the University Paris Diderot and the University of Helsinki (France and Finland) to develop computational and statistical approaches to improve the modeling of molecular recognition. This collaborative effort resulted in the development of different methods to predict protein pocket druggability, the extraction of phosphate local structural replacements, and better modeling of ionic molecular interactions between a ligand and a protein. 



"Science may be described as the art of systematic over-simplification"

-Karl Popper


2012 - 2016

Joint International Ph. D.

Computational Pharmaceutical Chemistry
and Biostatistics, Bionformatics

University Paris Diderot, Paris VII, France

University of Helsinki, Finland

2010 - 2012

Master's Degree in Bioinformatics

University Paris Diderot, Paris VII

2007 - 2010 

Bachelor's of Science in Biochemistry

University Paris Diderot, Paris VII


Thesis: Development of Computational Methods to Predict Protein Pocket Druggability and Profile Ligands using Structural Data (URN: ISBN:978-951-51-2174-5,

European action CM1207 STSM (2016)

    Research grant

Magnus Ehrnrooth’s foundation (2016)

    Graduate student fellowship

KAKSIN program (2013-2016)

    Mobility fellowship from French embassy 

To stay up-to-date with the latest research from the Fourches Lab or myself please follow me on LinkedIn, Twitter, ResearchGate or GitHub.

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